Whole30 / Paleo Mississippi Pot Roast Recipe
If you’re searching for the ultimate comfort food that fits your healthy eating goals, look no further than this Whole30 / Paleo Mississippi Pot Roast. This dish is impossibly tender, packed with bold flavors, and made from wholesome pantry staples—no processed packets needed! Each bite is cozy, savory, and tangy, thanks to a unique combination of spices, pepperoncini peppers, and slow-cooked beef. Whether you’re feeding a family, meal-prepping, or craving something hearty on a busy weeknight, this recipe delivers a truly satisfying experience while keeping things clean and compliant.

Ingredients You’ll Need
One of the best things about Whole30 / Paleo Mississippi Pot Roast is how a handful of simple, vibrant ingredients transform a humble chuck roast into an unforgettable meal. Here’s what you’ll need and why each one matters for building layers of flavor and melt-in-your-mouth texture.
- Beef chuck roast (3-5 lb): This cut is known for its richness and becomes incredibly tender when slow-cooked.
- Olive oil (2 tbsp): Helps create that gorgeous seared crust, locking in meat juices before slow cooking.
- Beef broth (1 cup): Adds depth, moisture, and serves as the base for a luscious pot roast sauce.
- Dried chives (1 tbsp): Brings a subtle oniony freshness without any harshness.
- Garlic powder (2 tsp): Delivers a savory backbone that works beautifully with the other spices.
- Onion powder (2 tsp): Adds another layer of sweetness and umami flavor.
- Dried dill (1 tsp): Lends a bright, herby note that makes the pot roast pop.
- Salt (1 tsp): Essential for balancing all the flavors and maximizing savoriness.
- Black pepper (1 tsp): Gives a warming bite that complements the slow-cooked beef.
- Pepperoncini peppers, whole (6-8): Bring signature tang and mild heat—don’t skip these!
- Pepperoncini pepper juice (1-2 tbsp): Just a splash kicks up the craveable, zesty finish.
- Ghee (4 tbsp): Adds richness and buttery flavor while keeping things Whole30 & Paleo friendly.
- Salt & pepper: Additional seasoning for depth and to taste as you go.
How to Make Whole30 / Paleo Mississippi Pot Roast
Step 1: Sear the Roast
Start by removing the beef chuck roast from the fridge and patting it dry—this helps guarantee a beautifully browned crust. Sprinkle all sides generously with salt and pepper. Heat the olive oil in a large skillet until shimmering hot, then carefully lay the roast in the pan. Let each side sizzle for 1 to 2 minutes until deeply golden. This step really is worth the extra couple minutes because it seals in the juices and sets the stage for that classic pot roast flavor.
Step 2: Deglaze with Broth
Once the roast is seared, transfer it to your slow cooker. You’ll notice glorious browned bits left behind in your skillet—this is pure flavor gold! Pour in the beef broth and use a wooden spoon to scrape up everything clinging to the pan. Simmer for 2-3 minutes until the liquid is reduced by half, then pour this aromatic broth right over the roast in the slow cooker. It infuses every bite with savory goodness.
Step 3: Add Spices and Pepperoncini
Sprinkle the dried chives, garlic powder, onion powder, dill, a bit more salt, and black pepper over the roast so they settle into every crevice. Nestle your pepperoncini peppers around the beef and drizzle in just a bit of pepper juice from the jar. Finish by dolloping ghee across the top—this melts down to make a flavor-packed sauce as it cooks. Cover tightly with the lid and set the slow cooker on low for 8 to 10 hours or high for 5 to 6 hours. You’ll know the Whole30 / Paleo Mississippi Pot Roast is ready when even a gentle poke with a fork makes the beef fall apart.
Step 4: Serve and Enjoy
Once your roast is meltingly tender, transfer it to a platter and shred with two forks, spooning some of that luscious cooking liquid over the top. Now you’ve got a famously irresistible Whole30 / Paleo Mississippi Pot Roast—divine on its own, or paired with your favorite cozy sides.
How to Serve Whole30 / Paleo Mississippi Pot Roast

Garnishes
The simplest garnish can take this dish from everyday to extraordinary. Some fresh chopped parsley or chives adds a pop of color and brightness. You can even scatter a few extra sliced pepperoncini on top for extra kick and visual flair. A drizzle of those pan juices right before serving makes sure every forkful is juicy and flavor-packed.
Side Dishes
Whole30 / Paleo Mississippi Pot Roast truly shines with creamy, comforting sides. Try it over fluffy mashed cauliflower or a pile of roasted root veggies to soak up the sauce. If you’re not strictly paleo, a scoop over traditional mashed potatoes will never disappoint. Lightly sautéed green beans or a fresh salad add something crisp to balance the richness of the roast.
Creative Ways to Present
Don’t be afraid to get playful! Stuff the shredded pot roast into baked sweet potatoes for a handheld meal, or wrap it in lettuce cups for a lighter take. Turn leftovers into hearty breakfast hash with crispy potatoes and eggs, or roll it into paleo tortillas for an unforgettable taco night. The robust flavors of Whole30 / Paleo Mississippi Pot Roast make it ultra-versatile for meal creativity.
Make Ahead and Storage
Storing Leftovers
Leftover Mississippi Pot Roast makes some of the best meal prep ever. Let the beef and juices cool a bit, then store airtight in the fridge for up to 4 days. Be sure to add enough of that broth for reheating, which will keep everything juicy and moist.
Freezing
To enjoy your Whole30 / Paleo Mississippi Pot Roast later, portion cooled roast and its juices into freezer-safe bags or containers. Label and freeze for up to 3 months. Thaw in the refrigerator overnight for best texture and flavor.
Reheating
Reheat thawed pot roast gently in a covered saucepan over low heat, adding a splash more broth if needed. For individual portions, the microwave works in a pinch—just cover and heat in short bursts, stirring halfway through. This keeps your beef fork-tender rather than dry.
FAQs
Can I make this Whole30 / Paleo Mississippi Pot Roast in the oven?
Absolutely! Use a Dutch oven or heavy roasting pan. Sear, assemble, and add all your ingredients as you would for the slow cooker. Cover tightly and roast at 300°F for about 3-4 hours, until the meat is falling apart.
Do I have to use ghee?
Ghee brings buttery richness while staying Whole30 and Paleo compliant, but you could substitute with coconut oil or another high-quality compatible fat if needed.
What if I can’t find pepperoncini peppers?
If pepperoncini are tricky to find, look for mild banana peppers or another mild pickled pepper. The tangy, slightly spicy flavor really defines the Mississippi Pot Roast experience.
Can I use a different cut of beef?
Chuck roast is ideal for tenderness and flavor, but brisket or a well-marbled shoulder roast would also work if that’s what you have on hand.
Is this kid-friendly despite the peppers?
Surprisingly, yes! The pepperoncini peppers are mild and mostly add zing rather than heat. If you’re concerned, you can reduce the number used or only add the pepper juice for subtle flavor.
Final Thoughts
If you’ve never tried Whole30 / Paleo Mississippi Pot Roast, now is the perfect time to treat yourself to a delicious, fuss-free meal that tastes as dreamy as it smells. Gather your ingredients, set it and forget it, and prepare to fall in love with pure comfort food that fits any healthy lifestyle!
PrintWhole30 / Paleo Mississippi Pot Roast Recipe
A comforting and flavorful Whole30 / Paleo Mississippi Pot Roast recipe that is perfect for a hearty and satisfying meal. This tender and juicy beef chuck roast is cooked low and slow with aromatic spices and pepperoncini peppers.
- Prep Time: 15 minutes
- Cook Time: 8 hours on low or 5 hours on high
- Total Time: 8 hours 15 minutes (on low) or 5 hours 15 minutes (on high)
- Yield: 6–8 servings 1x
- Category: Main Course
- Method: Slow Cooking
- Cuisine: American
- Diet: Paleo
Ingredients
For the Pot Roast:
- 3–5 lb beef chuck roast
- 2 tbsp olive oil
- 1 cup beef broth
- 1 tbsp dried chives
- 2 tsp garlic powder
- 2 tsp onion powder
- 1 tsp dried dill
- 1 tsp salt
- 1 tsp black pepper
- 6–8 pepperoncini peppers, whole
- 1–2 tbsp pepperoncini pepper juice (from the jar)
- 4 tbsp ghee
- Extra salt & pepper for seasoning
Instructions
- Prepare the Chuck Roast: Take the chuck roast out of the fridge, pat dry, season with salt and pepper, and sear in a hot skillet. Transfer to the slow cooker.
- Deglaze the Pan: After searing the roast, deglaze the pan with beef broth, scraping up the browned bits. Pour the liquid over the chuck roast in the slow cooker.
- Season and Cook: Add chives, garlic powder, onion powder, dill, salt, and pepper to the roast. Place pepperoncini peppers around the meat, add pepper juice, and top with ghee. Cook on low for 8-10 hours or high for 5-6 hours until fork-tender.
- Serve: Serve the pot roast over your choice of sides and enjoy!
Notes
- You can add more pepperoncini peppers for extra tangy flavor.
- Adjust the cooking time based on the size of your roast for optimal tenderness.
Nutrition
- Serving Size: 1 serving
- Calories: 420 kcal
- Sugar: 1g
- Sodium: 870mg
- Fat: 31g
- Saturated Fat: 13g
- Unsaturated Fat: 15g
- Trans Fat: 0g
- Carbohydrates: 2g
- Fiber: 0g
- Protein: 34g
- Cholesterol: 130mg
Keywords: Mississippi Pot Roast, Paleo Pot Roast, Whole30 Pot Roast, Chuck Roast Recipe